Rabbit anti-gamma-H2AX Antibody, Affinity Purified

Unconjugated

Antibody was affinity purified using an epitope specific to gamma-H2AX immobilized on solid support. Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.The epitope recognized by A300-081A maps to a region surrounding phosphorylated serine 140 of human histone H2AX using the numbering given in entry NP_002096.1 (GeneID 3014).

gamma-H2AX

Human

Rabbit

Surrounding serine 140

H2AX is a member of the histone H2A family. The four core histones involved in the formation of the nucleosome structure of compacted chromatin are H2A, H2B, H3, and H4. H2AX may function to facilitate DNA repair, and recent studies have shown that H2AX is required for the maintenance of genomic stability. Gamma H2AX is the phosphorylated form of H2AX that results in response to DNA damage.

IgG

Polyclonal

Antigen Affinity Purified

1000 µg/ml

Liquid

兔抗gamma-H2AX（磷酸化组蛋白）抗体，三柠檬酸盐/磷酸盐缓冲液（含0.09%叠氮化钠溶液）

H2AFX

IHC, Immunohistochemistry (IHC),Immunohistochemistry (IHC),WB, Western Blot (WB),Western Blot (WB),ICC-IF Immunocytochemistry-Immunofluoresence (ICC-IF),Immunocytochemistry-Immunofluoresence (ICC-IF)

Human, Mouse

H2A.X; H2A/X; H2AX; H2AX histone; histone H2A.x; histone H2AX

3014

P16104