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RUNX2 (27-K)

产品介绍
产品信息
宿主
鼠

简单描述
RUNX2 抗体 27-K 是小鼠单克隆 IgG2b, 在69篇文献中引用,提供 50 µg/0.5 ml免疫human物种的重组RUNX2推荐用于 mouse, rat 和 human 来源的RUNX2 WB, IP, IF, IHC(P) 和 ELISA检测看 RUNX2 (F-2): sc-390351,可查看有标记的 RUNX2 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790关于如何获取RUNX2 (27-K): sc-101145的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。目前,我们还没有完成RUNX2 抗体 (27-K)的首选二抗检测试剂的鉴定。这项工作正在进行中。
查看产品引用文献(69) The mammalian Runt-related transcription factor (RUNX) family comprises three members, RUNX1 (also designated AML-1, PEBP2αB, CBFA2), RUNX2 (also designated AML-3, PEBP2αA, CBFA1, Osf2) and RUNX3 (also designated AML-2, PEBPαC, CBFA3). RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX2 is essential for skeletal mineralization in that it stimulates osteoblast differentiation of mesenchymal stem cells, promotes chondrocyte hypertrophy and contributes to endothelial cell migration and vascular invasion of developing bones. Regulating RUNX2 expression may be a useful therapeutic tool for promoting bone formation. Mutations in the C-terminus of RUNX2 are associated with cleidocranial dysplasia syndrome, an autosomal-dominant skeletal dysplasia syndrome that is characterized by widely patent calvarial sutures, clavicular hypoplasia, supernumerary teeth, and short stature.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

组成成分
细胞分化相关转录因子抗体,磷酸盐缓冲液

基因

数据库链接
Entrez-Gene ID
860;12393

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货号:
sc-101145
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询价
50μg/0.5ml
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