
产品介绍
产品信息
宿主
mouse

简单描述
RUNX2抗体(C-12)是小鼠单克隆IgG1 κ, 在30篇文献中引用,规格为200 µg/ml免疫mouse物种的RUNX2的氨基酸294-363抗-RUNX2 抗体 (C-12) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 RUNX2; 也和以下物种反应,包括: 和 equine, bovine, porcine and canine抗-RUNX2 抗体 (C-12) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统可用于ChIP的TransCruz试剂(sc-390715 X, 200 µg/0.1 ml)关于如何获取RUNX2 (C-12): sc-390715的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP 是 RUNX2 Antibody (C-12) for WB and IHC(P) 的首选应用二抗。这个产品以套装形式提供 RUNX2 Antibody (C-12) (参照下方订购信息).
查看产品引用文献(30) The mammalian Runt-related transcription factor (RUNX) family comprises three members, RUNX1 (also designated AML-1, PEBP2αB, CBFA2), RUNX2 (also designated AML-3, PEBP2αA, CBFA1, Osf2) and RUNX3 (also designated AML-2, PEBPαC, CBFA3). RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX2 is essential for skeletal mineralization in that it stimulates osteoblast differentiation of mesenchymal stem cells, promotes chondrocyte hypertrophy and contributes to endothelial cell migration and vascular invasion of developing bones. Regulating RUNX2 expression may be a useful therapeutic tool for promoting bone formation. Mutations in the C-terminus of RUNX2 are associated with cleidocranial dysplasia syndrome, an autosomal-dominant skeletal dysplasia syndrome that is characterized by widely patent calvarial sutures, clavicular hypoplasia, supernumerary teeth, and short stature.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.Alexa Fluor® is a trademark of Molecul

克隆类别
Replacement monoclonal antibody for: sc-8566, sc-10758, sc-12488.

组成成分
急性粒细胞白血病3蛋白抗体、1.0ml磷酸缓冲盐溶液(含0.1%叠氮化钠和0.1%明胶)

基因

应用
反应种属
m, r, h

数据库链接
Entrez-Gene ID
860;12393

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