Salidroside

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Salidroside

品牌： Absin

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参数

分子式：

C₁₄H₂₀O₇

分子量：

300.30

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产品介绍

产品信息

抗原名称

mTOR

商品描述

Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata.

分子量

300.30

纯度

＞98%

可溶性

Ethanol : 4 mg/mL (13.32 mM)
DMSO ：56 mg/mL (186.5 mM)
Water ：55 mg/mL (183.2 mM)

外观

Off-White Solid

In vitro(体外研究)

Salidroside inhibits the growth of various human cancer cell lines in concentration- and time-dependent manners, and the sensitivity to salidroside is different in those cancer cell lines. Salidroside could cause G1-phase or G2-phase arrest in different cancer cell lines, meanwhile, salidroside resultes in a decrease of CDK4, cyclin D1, cyclin B1 and Cdc2, and upregulates the levels of p27(Kip1) and p21(Cip1). Salidroside also alleviates cell viability loss and apoptotic cell death induced by H(2)O(2) stimulation in cultured NGF-differentiated PC12 cells by activating ERK1/2 pathway and inhibiting caspase-3 activation. Salidroside activates the PI3K/Akt pathway resulting in protective effects against MPP(+)-induced apoptosis in PC12 cells, which may be used in the treatment of Parkinson's disease (PD).

In vivo(体内研究)

Salidroside (20, 50 and 100 mg/kg) protects liver tissue from the oxidative stress elicited by D-galactosamine and lipopolysaccharide.

背景

别名

红景天苷

分子式

C₁₄H₂₀O₇

CAS号

10338-51-9

制备和贮存

保存方式

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

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货号：

abs812950-2mg

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