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SERCA2 (F-1)

产品介绍
产品信息
宿主
mouse

简单描述
SERCA2抗体(F-1)是小鼠单克隆IgG1 κ, 在23篇文献中引用,规格为200 µg/ml特异性抗原位于human物种的SERCA2的N-terminus的氨基酸2-29之间抗-SERCA2 抗体 (F-1) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 SERCA2; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine抗-SERCA2 抗体 (F-1) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统关于如何获取SERCA2 (F-1): sc-376235的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。目前,我们还没有完成SERCA2 抗体 (F-1)的首选二抗检测试剂的鉴定。这项工作正在进行中。
查看产品引用文献(23) ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The sarcoplasmic reticulum of striated muscle is a specialized intracellular membrane system that plays a critical role in the contraction and relaxation of muscle. The SERCAs mediate Ca2+ uptake into intracellular stores. SERCA-mediated Ca2+ uptake induces and maintains muscular relaxation. The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue-dependent processing which is responsible for the generation of the SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle, and the SERCA2b isoform expressed in all cell types. The SERCA3 gene is not as well characterized and is found in non-muscle cells. SERCA2 plays an important part in regulating cardiac contractile function. SERCA3 is an isoform expressed in several cell types including platelets, lymphoid cells and mast cel

克隆类别
Replacement monoclonal antibody for: sc-8094, sc-8095.

基因

应用
反应种属
m, r, h

数据库链接
Entrez-Gene ID
488;11938

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