SHIP-1 (D-11)

mouse

SHIP-1抗体(D-11)是小鼠单克隆IgG1 κ, 在1篇文献中引用，规格为200 µg/ml特异性抗原位于mouse物种的SHIP-1的N-terminus的氨基酸5-27之间推荐用于 mouse, rat 和 human 来源的SHIP-1 p145 WB, IP, IF 和 ELISA检测看 SHIP-1 (P1C1): sc-8425，可查看有标记的 SHIP-1 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790m-IgG Fc BP-HRP and m-IgG1 BP-HRP 是 SHIP-1 Antibody (D-11) for WB首选应用二抗。这些试剂现在以套装形式提供SHIP-1 Antibody (D-11) (见下方订购信息). 查看产品引用文献(1) The major translational product of the v-Fms oncogene, originally isolated from the McDonough strain of feline sarcoma virus, has been identified as a glycoprotein with intrinsic tyrosine kinase activity. The v-Fms human cellular homolog, c-Fms, has been molecularly cloned and and identified as the receptor for hematopoietic ligand, CSF-1. Ligand-induced activation of the intrinsic CSF-1R protein tyrosine kinase triggers its interaction with cytoplasmic effector molecules. One such effector molecule, SHIP-1 p145 (SH2-containing-inositol phosphatase), associates with activated Fms. SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate polyphosphate 5-phosphatase activity. Evidence suggests that SHIP-1 may modulate Ras signaling in addition to inositol signaling pathways.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

HumanINPP5D