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hSIRPb1 A405 MAb (30 (100 UG)
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产品介绍
产品信息
耦联标记
Alexa Fluor 405
抗原名称
CD172 antigen-like family member B， CD172b antigen， CD172b， DKFZp686A05192， FLJ26614， signal-regulat
宿主
Mouse IgG1
克隆号
308908
Human SIRP beta 1/CD172b Alexa Fluor® 405-conjugated Antibody Summary
Species Reactivity
Human
Specificity
Detects human SIRP beta 1/CD172b in direct ELISAs.
Source
Monoclonal Mouse IgG1 Clone # 308908
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human SIRP beta 1/CD172b
Gly26-Ala369 (Arg53His and Ala363Pro)
Accession # O00241.4
Gly26-Ala369 (Arg53His and Ala363Pro)
Accession # O00241.4
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)
Applications
Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
Human Peripheral Blood Granulocytes
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
背景
别名
CD172 antigen-like family member B,CD172b antigen,CD172b,DKFZp686A05192,FLJ26614,signal-regulatory protein beta 1,signal-regulatory protein beta-1,SIRP beta 1,SIRPB1,SIRP-beta-1 isoform 3,SIRP-BETA-1,Signal-regulatory Protein beta 1
背景
Background: SIRP beta 1/CD172b
SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains. Unlike SIRP alpha that has cytoplasmic ITIM domains, SIRP beta 1 possesses positively charged residues that allow association with ITAM motif containing adaptor molecules. SIRP beta 1 is expressed on cells of monocyte, macrophage or dendritic lineages.
Long Name
Signal-regulatory Protein beta 1
Entrez Gene IDs
10326 (Human); 102139733 (Cynomolgus Monkey)
Alternate Names
CD172 antigen-like family member B; CD172b antigen; CD172b; DKFZp686A05192; FLJ26614; signal-regulatory protein beta 1; signal-regulatory protein beta-1; SIRP beta 1; SIRPB1; SIRP-beta-1 isoform 3; SIRP-BETA-1
研究领域
制备和贮存
保存方式
Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
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危险品化学品经营许可证(不带存储) 许可证编号：沪(杨)应急管危经许[2022]202944(QY) 
营业执照(三证合一)