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Src (L4A1) Mouse mAb

品牌： CST

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参数

分子量：

反应种属：

Human,Mouse,Rat,Monkey,

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产品介绍

产品信息

抗原名称

Src

来源纯化

Monoclonal antibody is produced by immunizing animals with a recombinant fusion protein containing an N-terminal fragment of human Src.

宿主

Mouse

简单描述

Monoclonal Antibody for studying Src. Cited in 126 publications. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in-house, Src (L4A1) Mouse Monoclonal Antibody (CST #2110) is ready to ship.

商品描述

Product Usage Information

Application	Dilution
Western Blotting	1:1000
Immunoprecipitation	1:50

分子量

内毒素水平

鸡

研究领域

癌症,代谢,神经科学

应用

反应种属

Human,Mouse,Rat,Monkey,

预测反应种属

Chicken,

目标/特异性

Specificity/Sensitivity

Src (L4A1) Mouse mAb detects endogenous levels of Src proteins. The antibody does not cross-react with other proteins.

Species Reactivity:

Human, Mouse, Rat, Monkey

敏感性

Endogenous

背景

The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2). 1.Thomas, S.M. and Brugge, J.S. (1997) Annu Rev Cell Dev Biol 13, 513-609. 2.Hunter, T. (1987) Cell 49, 1-4.

研究领域

癌症,代谢,神经科学

翻译后修饰

Unmodified

制备和贮存

保存方式

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

数据库链接

Entrez-Gene ID

6714

UniProt ID

P12931

参考图片

Western blot analysis of cell extracts from various cell lines, using Src (L4A1) Mouse mAb.

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货号：

2110S

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20μl

100ul

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