
产品介绍
产品信息
宿主
mouse

简单描述
抗-TAF II p68 抗体 TAF15B11A6 是小鼠单克隆 IgG1,TAF II p68抗体, 在2篇文献中引用,规格为100 µg/mlraised against a recombinant protein corresponding to a region near the N-terminus of TAF II p68 of human origin推荐用于 human 来源的TAF II p68 WB 和 IP检测关于如何获取TAF II p68 (TAF15B11A6): sc-81121的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。目前,我们还没有完成TAF II p68 抗体 (TAF15B11A6)的首选二抗检测试剂的鉴定。这项工作正在进行中。
查看产品引用文献(2) TAF II p68 Antibody (TAF15B11A6) is a high quality monoclonal TAF II p68 antibody (also designated TAF II p68 antibody) suitable for the detection of the TAF II p68 protein of human origin. TAF II p68 Antibody (TAF15B11A6) is available as the non-conjugated anti-TAF II p68 antibody. TFIID is a general transcription factor which initiates preinitiation complex assembly through direct interaction with the TATA promoter element. It is a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs). TAF II p68, also known as TAF15, RBP56 or TAF2N, is a member of the RNA polymerase II multiprotein complex and is present in certain TFIID subcomplexes. Expressed throughout the body, TAF II p68 is a single stranded RNA binding protein that shares homology with TLS (translocated in liposarcoma) and EWS (Ewing′s sarcoma), both of which are proto-oncogenes. Fusion of TAF II p68 with certain transcription factors transforms it into an oncoprotein with oncogenic potential at the N-terminus. When, for example, TAF II p68 is fused with TEC (translocated in extraskeletal chondrosarcoma), the fusion pair acts as an oncoprotein in which TAF II p68 is the transactivation domain. Defects in the gene encoding TAF II p68 are associated with extraskeletal myxoid chondrosarcoma, a malignant soft tumor.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-109061.

组成成分
IGG-免疫球蛋白G型抗体

基因

数据库链接
Entrez-Gene ID
8148

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