
产品介绍
产品信息
宿主
mouse

简单描述
Tara 抗体 2438C1a 是小鼠单克隆 IgG1, 在1篇文献中引用,提供 100 µg/mlraised against a recombinant protein corresponding to an internal region of Tara of human origin推荐用于 human 来源的Tara WB 和 IP检测目前,我们还没有完成Tara 抗体 (2438C1a)的首选二抗检测试剂的鉴定。这项工作正在进行中。
查看产品引用文献(1) Tara (Trio-associated repeat on actin), also known as TRIOBP (TRIO and F-actin-binding protein) or DFNB28, is a widely expressed protein with highest levels of expression in heart and placenta. Tara localizes to the nucleus and cytoplasm. It contains a pleckstrin homology domain at the N-terminus and a coiled-coil region at the C-terminus. Tara binds to and interacts with Trio, TRF1 and F-actin. Via these interactions, Tara plays a role in the development of neural tissue and the organization of the actin cytoskeleton. Tara functions to stabilize F-actin structures and therefore is also involved in the control of cell growth and motility. Mutations in the gene encoding this protein may result in autosomal recessive nonsyndromic sensorineural deafness type 28 (DFNB28). Five isoforms exist for Tara due to alternative splicing. Isoform 3, also known as the long isoform, is exclusively expressed in fetal retina, cochlea and brain.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-86899, sc-86900, sc-135422.

组成成分
IGG-免疫球蛋白G型抗体

基因

数据库链接
Entrez-Gene ID
11078

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