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Tau (Tau-13)

产品介绍
产品信息
宿主
鼠

简单描述
Tau抗体(Tau-13)是小鼠单克隆IgG1 κ, 在21篇文献中引用,规格为200 µg/mlraised against human recombinant Tau抗-Tau 抗体 (Tau-13) 推荐用于 WB, IP, IF 和 IHC(P),检测mouse, rat 和human 来源的 all Tau isoforms; not inhibited by Tau phosphorylation抗-Tau 抗体 (Tau-13) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统另提供生物素偶联抗体,可用于WB、IHC(P)和ELISA实验关于如何获取Tau (Tau-13): sc-21796的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 Tau Antibody (Tau-13) for WB and IHC(P) 的首选应用二抗。这些试剂现在以套装形式提供Tau Antibody (Tau-13)。 (见下方订购信息).
查看产品引用文献(21) Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to the cytoskeleton and the cell membrane, and contains four Tau/MAP repeats. Expressed in neuronal tissue and existing as multiple alternatively spliced isoforms, Tau functions to promote microtubule assembly and stability and is thought to be involved in the maintenance of neuronal polarity. Tau may also link microtubules with neural plasma membrane components and, addition to its role in microtubule stability, is also necessary for cytoskeletal plasticity. Tau is highly subject to a variety of post-translational modifications, including phosphorylation on serine and threonine residues, polyubiquitination (and subsequent proteasomal degradation) and glycation of specific Tau isoforms. Defects in the gene encoding Tau are associated with Alzheimers disease, pallido-ponto-nigral degeneration (PPND), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP).For Research Use Only. Not Intended

组成成分
微管相关蛋白抗体,磷酸盐缓冲液

基因

应用
实验应用
WB, IP, IF, IHC(P)

数据库链接
Entrez-Gene ID
4137;17762

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