TNF-α Protein, Rabbit

1/2

TNF-α Protein, Rabbit

品牌： UA BIOSCIENCE

下载产品说明书

用小程序，查商品更便捷

对比

咨询

参数

分子量：

17.5kDa (Reducing)

纯度：

＞95% by SDS-PAGE

产品介绍

产品信息

耦联标记

Unconjugated

氨基酸序列

Val78-Leu235

分子量

17.5kDa (Reducing)

生物活性

< 5pg/ml

纯度

＞95% by SDS-PAGE

内毒素水平

<0.1EU/μg

性状

Lyophilized Powder

表达系统

E.coli

缓冲体系

PBS, pH7.4.

标签

No Tag

种属

Rabbit

电泳JSON

[{"imgUrl":"https://univ-pmc.oss-cn-shanghai.aliyuncs.com/product.imager.attribute/0/dc414996-e273-4a93-8818-e695512f4787.png","description":"

\n1μg (R: reducing\ncondition, N: non-reducing condition).\n\n\n\n

"}]

背景

别名

Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2 (TNF-a)

背景

Tumor Necrosis Factor alpha (TNF-α), is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. TNF-α exerts many of its effects by binding to either a 55 kDa cell membrane receptor termed. TNF-α activates signals through two receptors, TNF-R1, which is expressed on most cell types, and TNF-R2, which is expressed mainly on immune cells. TNF-α can have many functions including, to stimulate of phagocytosis in macrophages, to chemoattract neutrophils, to increase insulin resistance and to induce fever.

制备和贮存

溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

保存方式

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

文献

1.D Pennica, et al. (1984) Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature.312(5996):724-9. DOI: 10.1038/312724a0.

2. S A Nedospasov, et al. (1986) Tandem arrangement of genes coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) in the human genome. Cold Spring Harb Symp Quant Biol.51(1) 1:611-24. DOI: 10.1101/sqb.1986.051.01.073.

数据库链接

Accession

P04924

参考图片

1μg (R: reducing condition, N: non-reducing condition).

Measured in a cell proliferation assay using L-929 mouse fibrosarcoma cells, the EC50 for this effect is less than 5pg/ml.

声明：本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。

货号：

UA040135-1mg

一键复制

询价

优宁维现货

1mg

10μg

50μg

100μg

500μg

选择数量

当前规格1件起购

配送至

预计2-5个工作日送达，快递: 免运费，若需干冰额外收费

询价大包装询价