


1/2
产品介绍
产品信息
宿主
鼠

克隆号
DC101

克隆类别
单抗

Product Details
The DC101 monoclonal antibody reacts with mouse VEGFR-2 (vascular endothelial growth factor receptor 2) also known as CD309, KDR, and Flk-1. VEGFR-2 is a member of the tyrosine protein kinase family. Upon binding to its ligand VEGF, VEGFR-2 pays key roles in vascular development and permeability. VEGFR-2 is expressed on endothelial cells at high levels in adult heart, lung, kidney, brain, and skeletal muscle as well as other tissues at lower levels. The DC101 antibody has been shown to inhibit VEGFR-2 signaling in vivo.Specifications
Isotype | Rat IgG1, κ |
---|---|
Recommended Isotype Control(s) | InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase |
Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
Immunogen | Mouse VEGFR-2-SEAPs soluble receptor |
Reported Applications | in vivo blocking of VEGF/VEGFR-2 signaling in vitro blocking of VEGFR signaling Western blot |
Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
Purity | >95% Determined by SDS-PAGE |
Sterility | 0.2 µm filtration |
Production | Purified from cell culture supernatant in an animal-free facility |
Purification | Protein G |
RRID | AB_1107766 |
Molecular Weight | 150 kDa |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
血管内皮生长因子受体2蛋白抗体,磷酸盐缓冲液

应用
反应种属
mouse

背景
研究领域
Cancer Biology, Cell Migration & Adhesion, Neuroscience, Tumor Antigens
声明 :本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。