InVivoMAb anti-mouse VEGFR-2
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InVivoMAb anti-mouse VEGFR-2

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品牌: BioXcell
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    反应种属:
    mouse
    mouse
    来源宿主:
    产品介绍
    产品信息
    宿主
    克隆号
    DC101
    克隆类别
    单抗

    Product Details

    The DC101 monoclonal antibody reacts with mouse VEGFR-2 (vascular endothelial growth factor receptor 2) also known as CD309, KDR, and Flk-1. VEGFR-2 is a member of the tyrosine protein kinase family. Upon binding to its ligand VEGF, VEGFR-2 pays key roles in vascular development and permeability. VEGFR-2 is expressed on endothelial cells at high levels in adult heart, lung, kidney, brain, and skeletal muscle as well as other tissues at lower levels. The DC101 antibody has been shown to inhibit VEGFR-2 signaling in vivo.

    Specifications

    Isotype Rat IgG1, κ
    Recommended Isotype Control(s)InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase
    Recommended Dilution BufferInVivoPure pH 7.0 Dilution Buffer
    Conjugation This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
    Immunogen Mouse VEGFR-2-SEAPs soluble receptor
    Reported Applicationsin vivo blocking of VEGF/VEGFR-2 signaling
    in vitro blocking of VEGFR signaling
    Western blot
    Formulation PBS, pH 7.0
    Contains no stabilizers or preservatives
    Endotoxin <2EU/mg (<0.002EU/μg)
    Determined by LAL gel clotting assay
    Purity >95%
    Determined by SDS-PAGE
    Sterility 0.2 µm filtration
    Production Purified from cell culture supernatant in an animal-free facility
    Purification Protein G
    RRIDAB_1107766
    Molecular Weight 150 kDa
    Storage The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
    组成成分
    血管内皮生长因子受体2蛋白抗体,磷酸盐缓冲液
    应用
    反应种属
    mouse
    背景
    研究领域
    Cancer Biology, Cell Migration & Adhesion, Neuroscience, Tumor Antigens
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    货号:
    BE0060-1MG
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