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hGLP-1 MAb (Cl 2622G (25 UG)

品牌： R&D Systems

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来源宿主：

Rabbit IgG

产品介绍

产品信息

耦联标记

Unconjugated

抗原名称

glicentin-related polypeptide， GLP1， GLP-1， glucagon-like peptide 1， GRPP

宿主

Rabbit IgG

克隆号

2622G

Human GLP-1 Antibody Summary

Species Reactivity

Human

Specificity

Detects human GLP-1 in direct ELISAs.

Source

Recombinant Monoclonal Rabbit IgG Clone # 2622G

Purification

Protein A or G purified from cell culture supernatant

Immunogen

Human GLP-1 synthetic peptide
Accession # P01275

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

ELISA

This antibody functions as an ELISA detection antibody when paired with Rabbit Anti-Human GLP-1 Monoclonal Antibody (Catalog # MAB124901).

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

背景

别名

glicentin-related polypeptide,GLP1,GLP-1,glucagon-like peptide 1,GRPP,Glucagon-like Peptide 1

背景

Background: GLP-1

Glucagon is a preprotein which is cleaved into four distinct peptides, including the hormone GLP-1 (aa 98-128). GLP-1 is a secreted hormone with multiple effects upon the intestine (gastric motility), pancreas (glucose dependent insulin release) and hypothalamic pituitary axis (modulates LH, THS, CRH, ocytocin and vasopressin secretion). It also affects plasma glucagon levels. GLP-1 is expressed in enteroendocrine L cells and neurons of the caudal brainstem which project to the forbain, the amygdala and the hypothalamus. Recent studies show pancreatic intra-islet GLP-1 expression, which is regulated by cytokines, hyperglycemia and cell injury.

Long Name

Glucagon-like Peptide 1

Entrez Gene IDs

2641 (Human)

Alternate Names

glicentin-related polypeptide; GLP1; GLP-1; glucagon-like peptide 1; GRPP

研究领域

Related Research Areas

制备和贮存

保存方式

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

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货号：

MAB12490-SP

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询价

25UG

100UG

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